WHO South-East Asia Journal of Public Health
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Year : 2014  |  Volume : 3  |  Issue : 1  |  Page : 36-40

Co-circulation of dengue virus serotypes with chikungunya virus in Madhya Pradesh, central India

1 Regional Medical Research Centre for Tribals (ICMR), Jabalpur, Madhya Pradesh, India
2 Netaji Subhash Chandra Bose Medical Collage, Jabalpur, Madhya Pradesh, India

Correspondence Address:
Neeru Singh
Regional Medical Research Centre for Tribals (Indian Council of Medical Research), Nagpur Road, Post Garha, Jabalpur 482003, Madhya Pradesh
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DOI: 10.4103/2224-3151.206881

PMID: 28607252

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Background:Dengue and chikungunya present with very similar signs and symptoms in the initial stage of illness and so it is difficult to distinguish them clinically. Both are transmitted by Aedes aegypti and Aedes albopictus mosquitoes. This study was conducted with the aim to explore the co-circulation of dengue and chikungunya viruses in central India. Materials and methods:Samples from suspected dengue cases were subjected to dengue immunoglobulin M (lgM) enzyme-linked immunosorbent assay (ELISA) and dengue-negative samples were tested with chikungunya-specific IgM ELISA. The samples collected in acute phase of illness were tested by nested reverse transcription polymerase chain reaction (nRT-PCR). Chikungunya virus (CHIKV) sequences were analysed to determine their genotype. Results:Of 138 samples screened for dengue, 21 (15.2%) were positive, and of 119samples screened for chikungunya, 13 (10.9%) were positive. Dengue viruses 1 and 4 were found co-circulating with chikungunya virus in Jabalpur, central India. The chikungunya virus detected belonged to the East Central South African genotype. Conclusion:Accurate and timely diagnosis would help in patient management and use of resources. It is advocated to simultaneously test samples for these two diseases in endemic areas. This will also aid in understanding the epidemiology of chikungunya.

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