WHO South-East Asia Journal of Public Health
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REVIEW
Year : 2013  |  Volume : 2  |  Issue : 1  |  Page : 23-27

Changing epidemiology of dengue in South-East Asia


1 Department of Communicable Diseases, World Health Organization/South East Asia Regional Office (SEARO), New Delhi, India
2 Department of Communicable Diseases, World Health Organization/South East Asia Regional Office (SEARO); Medical Coordinator, MSF Spain, New Delhi, India

Correspondence Address:
Temmy Sunyoto
Medical Coordinator, MSF Spain, C-203 Defence Colony, New Delhi
India
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DOI: 10.4103/2224-3151.115830

PMID: 28612819

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The burden of dengue and its potential threat to global health are now globally recognized, with 2.5 billion people at risk worldwide. The pathogenesis of severe dengue is particularly intriguing with the involvement of different immune factors. Also, the epidemiology of dengue in South-East Asia is undergoing a change in the human host, the dengue virus and the vector bionomics. Shift in affected age groups, sex differences and expansion to rural areas are evident, while the virulence and genotype of the virus determine the severity and time interval between sequential infections. The Aedes mosquito, a potent and adaptive vector, has evolved in longevity and survival, affected by seasonality and climate variability, socio-cultural and economic factors of human habitation and development. This review provides insights into the changing epidemiology and its factors in South-East Asia, one of the most important epicentres of dengue in the world, highlighting the major factors influencing these rapid changes. Addressing the changes may help mitigate the challenges in the current dengue control and prevention efforts.


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